Appendix A:

List of referral centres – Cellular Pathology Department SHYPS

Address Referral Repertoire Reason for Selection Accreditation
Cellular Pathology,
Queen Elizabeth Hospital,
Mindelsohn Way,
Edgebaston,
BIRMINGHAM
B15 2WB
CKIT, ROS1 and ALK FISH This was the centre of the trials of these tests prior to approval by NICE

They have a long history, give good service & have good audit data

UKAS: 8759
Histopathology Dept
Nottingham City Hospital
Hucknall Road
Nottingham
NG5 1PB
Referral of rare and difficult breast pathology cases The regional centre UKAS: 8162
North East & Yorks Genomic Laboratory Hub
Central Lab
St James’s University Hospital
Ashley Wing
LEEDS
LS9 7TF
Molecular testing The regional centre UKAS: 8096
SMDS Histology Laboratory, Bexley Wing, St James Institute of Oncology, Beckett Street Sarcoma Diagnosis Specialist Centre
HMDS. Department of Pathology,
Level 5
Bexley Wing
St James Institute of Oncolocy
Beckett Street
LEEDS
LS9 7TF
Lymphoma diagnosis

Haematological diseases

Specialist referral centre of Yorkshire UKAS: 9305
Genomic Health,
301 Penobscot Drive,
Redwood City,
CA 94063
USA
For Oncotype DX Requested by HUTH breast surgeons N/A
Leeds Molecular Mycobacteriology Unit,
Department of Microbiology,
The General Infirmary,
LEEDS
LS1 3EX
PCR for TB The regional centre UKAS: 8157
Manchester Royal Infirmary,
Oxford Road,
Manchester
M13 9WL
Electron Microscopy and IHC staining and BRCA and HRD testing Covers IHC stains which are not covered in our repertoire or other referral laboratories

Also, Oncologists choice for Hull patients

Mitochondrial Research Group,
4th Floor (The Medical School),
University of Newcastle upon Tyne,
Framlington Place,
Newcastle upon Tyne
NE2 4HH
Mitochondrial diseases NSCAG-funded reference centre for the diagnosis of mitochondrial diseases UKAS: 9027
Muscle Immunoanalysis Unit,
Lower Ground Floor,
Dental Hospital,
Richardson Road,
Newcastle upon Tyne
NE2 4AZ
Non-mitochondrial neuromuscular diseases NSCAG-funded reference centre for the diagnosis of non-mitochondrial diseases UKAS:9028
(Location code: B)
National Amyloidosis Centre,
Royal Free Hospital,
LONDON
NW3 2PF
Amyloid analysis National centre for this work Awaiting update.
National Centre for Mineral & Fibre Analysis,
University of Wales Hospital,
CARDIFF
CF10 3NS
Asbestos fibre analysis National centre for this work UKAS: 8987
National Specialist Ophthalmic Pathology service,
Department of Histology,
E-Floor,
Royal Hallamshire Hospital,
Glossop Road,
SHEFFIELD
S10 2JF
All ocular work excluding skin which are done in-house NSCAG-funded reference centre for the diagnosis of ocular disease UKAS: 8509
Neuropathology,
The National Hospital for Neurology and Neurosurgery,
Queen’s Square,
LONDON
WC1N 3BG
Referral of rare and difficult lesions Runs the diagnostic EQA scheme. Have specialist pathologists

Referral service for Neuropathology

UKAS: 8116
Histopathology Department,
Royal Hallamshire Hospital,
Glossop Road,
Sheffield
S10 2JF
Reporting of GIT specimens

EM samples

Reciprocal agreement for reporting GIT specimens and SEYN Neuropathology UKAS: 8509
SourceLDPath UK Ltd,
1 Orchard Place,
Nottingham Business Park,
NOTTINGHAM
NG8 6PX
Outsourced reporting Recognised supplier of this service and UKAS accredited UKAS: 9571
Deptartment Of Musculoskeletal Pathology,
Royal Orthopaedic Hospital
Robert Aitken Institute of Clinical Research,
University of Birmingham Vincent Drive,
BIRMINGHAM
B15 2TT
Musculoskeletal second opinions Specialist centre for Musculoskeletal pathology UKAS: 9897
Backlogs Limited,
Silvaco Technology Centre,
Compass Point,
ST IVES
PE27 5JL
Outsourcing reporting Recognised supplier of this service and UKAS accredited UKAS: 21408
Health Services Laboratories (HSL),
Advanced Diagnostics,
Ground Floor,
60 Whitfield Street,
LONDON
WIT 4EU
IHC, FISH and CISH staining They have a larger repertoire of IHC stains and FISH/CISH probes which are not available in-house or through our other referral laboratories UKAS: 9007
Clinical Genomics,
The Royal Marsden,
NHS FT,
15 Cotswold Road,
SUTTON
SM2 5MG
BRCA and HRD testing Oncologists choice – Scunthorpe patients UKAS: 20653

Appendix B:

List of locations and personnel for second opinions – Cellular Pathology Department SHYPS

Address Referral Repertoire Reason for Selection Accreditation
Fletcher Consult Service
Brigham & Womens Hospital,
75 Francis Street,
Boston,
Massachussetts
MA 02115
(617) 732-8558
Second opinion Expert in soft tissue work and urology and does not charge Joint commission laboratory accreditation program (ID #5503)
Genomic Health,
301 Penobscot Drive,
Redwood City,
CA 94063
USA
customerservice@genomichealth.com
For Oncotype DX Trust has a contract with them as they are the only ones whose test is NICE approved CAP: 7186524
ISO 15189 3922.01
Prof S Lucas / Dr E Calonje,
Viapath Analytics Ltd,
Guys & St Thomas Hospital,
Westminster Bridge Road,
LONDON
SE1 7EG
sebastian.lucas@gstt.nhs.uk
Second opinion Expert in Tropical Pathology UKAS Accredited to ISO 18159:2012

(ref number 9323)

Prof A Nicholson/ Dr A Rice,
Royal Brompton,
Sydney Street,
LONDON
SW3 6NP
Second opinion Expert in cardiothoracic
pathology
UKAS Accredited to ISO 18159:2012

(ref number 8818)

Professor M Cook,
Royal Surrey County Hospital,
Egerton Road,
GUILFORD
GU27 7XX
01483 464065
Second opinion National lead in skin pathology UKAS Accredited to ISO 18159:2012 (ref number: 9727)
Dr B Mathew,
Department of Histopathology and Molecular Pathology,
Level 5,
Bexley Wing,
St Jame’s Institute of Oncology,
Beckett Street,
LEEDS
LS9 7TF
Bipin.Mathew@nhs.net
Second opinion Specialist dermatopathologist and expert in sarcoma cases UKAS accredited to ISO 18159:2012 (ref number: 9862)
Professor E Rakha,
Nottingham City Hospital,
Hucknall Road,
NOTTINGHAM
NG5 1PB
Emad.Rakha@nottingham.ac.uk
Second opinion National expert in Breast pathology UKAS accredited to ISO 18159:2012 (ref number: 8162)
Dr Awatif Al-Nafussi and Professor William Wallace,
Department of Pathology,
Royal Infirmary of Edinburgh,
51 Little France Crescent,
EDINBURGH
EH16 4SA
a.alnafussi@ed.ac.uk
Second opinion Dr Al Nafussi is expert in soft tissue and gynaecological pathology.
Dr Wallace is expert in Cardiothoracic pathology
UKAS accredited to ISO 18159:2012 (ref number: 9546)
Dr J Wyatt,
Department of Histopathology and Molecular Pathology,
Level 5,
Bexley Wing,
St Jame’s Institute of Oncology,
Beckett Street,
LEEDS
LS9 7TF
judy.wyatt@nhs.net
Second opinion Expert in liver transplant pathology UKAS accredited to ISO 18159:2012 (ref number: 9862)
Dr Candice Roufosse,
North West London Pathology,
Cellular Pathology,
3rd Floor Charing Cross Hospital (Lab Block),
Fulham Palace Road
LONDON
W6 8RF
Second opinion The only centre for immunocytochemistry stain DNAJB9 on renal biopsies UKAS accredited to ISO 15189:2012 (ref number: 9615)
Professor I Roberts Level 1,
West Wing,
John Radcliffe Hospital,
Headley Way,
Headington,
OXFORD
OX3 9DU
Second opinion Expert in renal pathology UKAS accredited to ISO 15189:2012 (ref number: 9642)
Imperial College Healthcare NHS Trust operating as North West London Pathology Department of Histopathology

Fulham Palace Road,

LONDON

W6 8RF

Second opinion Performs immunocytochemistry stains which are not in our repertoire UKAS accredited to ISO 15189:2012 (ref number: 9642)
Prof. Dr. Med. Abbas Agaimy,
Leitender Oberarzt,
Institute für Pathologie,
Universitäsklinikum Erlangen,
Krankenhausstrasse 8-10,
91054 Erlangen,
GERMANY
Second opinion Expert in soft tissue, GI and Head and Neck pathology Awaiting update
Professor Jonathan Epstein,
The John Hopkins Hospital,
1620 McElderry Street,
Room 315, Reed Hall,
Baltimore MD 21205,
USA
Second opinion Specialist in prostate biopsies specifically and urology in general. CAP accredited
CAP number: 1353003
AUD-ID: 1008617
CLIA Number: 21D0709511